Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533686 | 0.90 | PLA2G4A (0.33) | KDM4E | |
| SCHEMBL11531229 | 0.87 | MLYCD (0.40) | TP53GAAHPGDTSHRMEN1 | |
| SCHEMBL11531654 | 0.85 | TP53 (0.38) | TP53NPC1RAB9A | |
| SCHEMBL11525879 | 0.84 | TP53 (0.34) | TP53KDM4ELMNAGAAMEN1 | |
| SCHEMBL11531866 | 0.83 | LMNA (0.39) | TP53KDM4ELMNAHPGDL3MBTL1 | |
| SCHEMBL11529771 | 0.83 | TP53 (0.33) | TP53 | |
| SCHEMBL11530114 | 0.82 | TP53 (0.44) | TP53LMNAHTTMEN1KMT2A | |
| SCHEMBL11530811 | 0.82 | SMN1; SMN2 (0.34) | KDM4ETSHR | |
| SCHEMBL11531155 | 0.81 | ALDH1A1 (0.36) | TP53KDM4ELMNAMAPT | |
| SCHEMBL11528434 | 0.81 | ELANE (0.36) | TP53KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4143047-A | 2-SULFINYL AND 2-SULFONYL OXAZOLES | LILLY INDUSTRIES LIMITED (GB) | 1979-03-06 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |