Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530906 | 0.90 | PLA2G4A (0.33) | PLA2G4A | |
| SCHEMBL11529943 | 0.90 | ELANE (0.36) | ALDH1A1 | |
| SCHEMBL11528881 | 0.89 | KDM5A (0.36) | PLA2G4AALDH1A1 | |
| SCHEMBL11528434 | 0.86 | ELANE (0.36) | ALDH1A1KDM4E | |
| SCHEMBL11531654 | 0.84 | TP53 (0.38) | ALDH1A1 | |
| SCHEMBL11533073 | 0.84 | GPR84 (0.41) | ALDH1A1 | |
| SCHEMBL11528080 | 0.83 | LTB4R2 (0.46) | — | |
| SCHEMBL11534629 | 0.81 | MLYCD (0.35) | ALDH1A1 | |
| SCHEMBL11533525 | 0.81 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL11530712 | 0.80 | ALDH1A1 (0.37) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4143047-A | 2-SULFINYL AND 2-SULFONYL OXAZOLES | LILLY INDUSTRIES LIMITED (GB) | 1979-03-06 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |