Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942928 | 0.92 | NPC1 (0.45) | NPC1RAB9AKMT2AMAPK1TDP1 | |
| SCHEMBL7727468 | 0.89 | KMT2A (0.39) | NPC1RAB9AKMT2AMAPK1TDP1 | |
| SCHEMBL27912037 | 0.88 | CYP3A4 (0.41) | NPC1RAB9AKMT2AMAPK1TDP1 | |
| SCHEMBL27873 | 0.84 | TDP1 (0.54) | NPC1RAB9AKMT2AMAPK1TDP1 | |
| SCHEMBL10615043 | 0.84 | TDP1 (0.54) | NPC1RAB9AKMT2AMAPK1TDP1 | |
| SCHEMBL29849714 | 0.83 | AGXT (0.40) | MAPK1TDP1CYP3A4TRPA1 | |
| SCHEMBL29849567 | 0.83 | AGXT (0.40) | MAPK1TDP1CYP3A4TRPA1 | |
| SCHEMBL29849778 | 0.83 | TDP1 (0.39) | NPC1RAB9AKMT2AMAPK1TDP1 | |
| SCHEMBL30365208 | 0.82 | TDP1 (0.48) | KMT2AMAPK1TDP1CYP3A4TRPA1 | |
| SCHEMBL894324 | 0.82 | TDP1 (0.48) | KMT2AMAPK1TDP1CYP3A4TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1505 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119912405-A | Fluothidiazuron derivative and preparation method thereof | 河南省科学院高新技术研究中心 | 2025-05-02 | — | — | CN | claimed |
| CN-119859503-A | Heat-conducting adhesive and preparation method thereof | 深圳日高胶带新材料有限公司 | 2025-04-22 | — | — | CN | claimed |
| CN-107176925-B | Synthesis method of polysubstituted imidazoline-2, 4-diketone compound | 湖北科技学院 | 2020-04-28 | — | — | CN | claimed |
| CN-107176925-A | A kind of synthetic method of the cyclohexadione compounds of polysubstituted imidazoline 2,4 | 湖北科技学院 | 2017-09-19 | — | — | CN | claimed |
| EP-1754705-A2 | Antagonists for treatment of CD11/CD18 adhesion receptor mediated disorders | Genentech, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| EP-4713378-A1 | ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS | Covestro Deutschland AG (DE) | 2026-03-25 | — | — | EP | disclosed |
| US-12577373-B2 | Carbodiimide composition, curing agent composition, coating composition and resin cured product | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2026-03-17 | — | — | US | disclosed |
| US-20260042765-A1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | INCYTE CORP (US) | 2026-02-12 | — | — | US | disclosed |
| US-12479850-B2 | Compound having Axl and c-Met kinase inhibitory activity, preparation thereof and application thereof | SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) | 2025-11-25 | — | — | US | disclosed |
| EP-4642461-A1 | COMPOSITIONS FOR PREVENTING AND TREATING RENAL FAILURE (RF) | Chong Kun Dang Pharmaceutical Corp. (KR) | 2025-11-05 | — | — | EP | disclosed |
| EP-4638427-A1 | AMIDINOUREA DERIVATIVES AND THEIR USE IN THE TREATMENT OF CANCER | Université Côte d'Azur (FR) | 2025-10-29 | — | — | EP | disclosed |
| US-20250319093-A1 | COMPOSITIONS FOR PREVENTING OR TREATING IDIOPATHIC PULMONARY FIBROSIS (IPF) | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2025-10-16 | — | — | US | disclosed |
| US-4032638-A | Heterocyclic ureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-06-28 | — | — | US | disclosed |
| US-4001305-A | POLYURETHANES, OIL AND WATER REPELLANT, MOLD-RELEASE | CIBA-GEIGY CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-3998958-A | Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-12-21 | — | — | US | disclosed |
| US-3992535-A | ANTIINFLAMMATORY AGENTS, INHIBITORS OF PLATELET ADHESION AND AGGREGATION | BOEHRINGER INGELHEIM GMBH (DT) | 1976-11-16 | — | — | US | disclosed |
| US-3973946-A | Substituted-3-phenyl ureas | E. I. DUPONT DE NEMOURS & COMPANY (US) | 1976-08-10 | — | — | US | disclosed |
| US-3961061-A | INSECTICIDES, FUNGICIDES, BACTERICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-06-01 | — | — | US | disclosed |
| US-3935277-A | OIL AND WATER REPELLENT INTERMEDIATES | CIBA-GEIGY CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250319093-A1 | COMPOSITIONS FOR PREVENTING OR TREATING IDIOPATHIC PULMONARY FIBROSIS (IPF) | CFTR, MMP1, MACF1 | NPC1 1415/4885RAB9A 1880/4885KMT2A 4744/4885 |
| US-20260042765-A1 | PYRROLOTRIAZINE COMPOUNDS AS TAM INHIBITORS | MAP2K2, TTK, MAP2K5 | NPC1 4002/4885RAB9A 1162/4885KMT2A 806/4885 |
| US-12577373-B2 | Carbodiimide composition, curing agent composition, coating composition and resin cured product | CD38, PARP9, MCCC2 | NPC1 4413/4885RAB9A 2004/4885KMT2A 182/4885 |
| US-12479850-B2 | Compound having Axl and c-Met kinase inhibitory activity, preparation thereof and application thereof | MET, MERTK, AXL | NPC1 3655/4885RAB9A 2213/4885KMT2A 2069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.