Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7667098 | 0.80 | MKNK1 (0.41) | ALDH1A1L3MBTL1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11767314 | 0.79 | HPGD (0.41) | ALDH1A1HPGDMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL5136604 | 0.78 | LMNA (0.40) | LMNAALDH1A1L3MBTL1HPGDMTNR1A | |
| Fluoride SCHEMBL11728897 | 0.78 | HPGD (0.39) | ALDH1A1HPGDMTNR1AMTNR1BSMN1; SMN2 | |
| SCHEMBL11528331 | 0.77 | SMN1; SMN2 (0.40) | LMNAALDH1A1L3MBTL1HPGDMTNR1A | |
| SCHEMBL2981447 | 0.76 | SCN2A (0.40) | ALDH1A1L3MBTL1HPGDMTNR1AMTNR1B | |
| SCHEMBL4522173 | 0.76 | ALDH1A1 (0.38) | LMNAALDH1A1L3MBTL1HPGDMTNR1A | |
| SCHEMBL11092905 | 0.76 | HPGD (0.38) | LMNAALDH1A1HPGDMTNR1AMTNR1B | |
| SCHEMBL7662484 | 0.73 | HDAC1 (0.39) | ALDH1A1SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL11528821 | 0.72 | KMT2A (0.42) | ALDH1A1NPC1RAB9AKMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156735-A | SALIDIURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| US-4118501-A | SALIDIURETIC ACTIVITY | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |