Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11530416 | 0.87 | ALDH1A1 (0.50) | KMT2AALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL11529838 | 0.85 | AKR1C3 (0.53) | KMT2AALDH1A1GRIN2CMAPTHCAR3 | |
| SCHEMBL11533835 | 0.80 | LMNA (0.40) | KMT2AALDH1A1KCNMA1MAPTMAPK1 | |
| SCHEMBL11532438 | 0.79 | ALDH1A1 (0.52) | KMT2AALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL11530537 | 0.77 | ALDH1A1 (0.43) | KMT2AALDH1A1KCNMA1MAPTHCAR3 | |
| SCHEMBL11532019 | 0.77 | KMT2A (0.44) | KMT2AALDH1A1KCNMA1MAPTAKR1C3 | |
| SCHEMBL11530571 | 0.77 | ALDH1A1 (0.54) | KMT2AALDH1A1MAPTTDP1MEN1 | |
| SCHEMBL11532884 | 0.76 | AKR1C3 (0.53) | KMT2AALDH1A1KCNMA1MAPTAKR1C3 | |
| SCHEMBL11535384 | 0.75 | ALDH1A1 (0.56) | KMT2AALDH1A1MAPTMAPK1TDP1 | |
| SCHEMBL11530538 | 0.74 | ALDH1A1 (0.50) | KMT2AALDH1A1MAPTTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172831-A | CENTRAL NERVOUS SYSTEM | LILLY INDUSTRIES LIMITED (GB) | 1979-10-30 | — | — | US | disclosed |
| US-4115568-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |
| US-4115574-A | CNS ACTIVITY | LILLY INDUSTRIES LIMITED (GB) | 1978-09-19 | — | — | US | disclosed |