Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532121 | 0.93 | GLO1 (0.45) | ALDH1A1CYP2D6SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL11533251 | 0.84 | L3MBTL1 (0.40) | ALDH1A1MEN1KMT2AGAAPOLB | |
| SCHEMBL11530276 | 0.82 | CYP2C9 (0.43) | ALDH1A1SMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL10375705 | 0.79 | CYP2D6 (0.53) | ALDH1A1CYP2D6SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL11531594 | 0.78 | POLB (0.40) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL8944648 | 0.77 | MEN1 (0.53) | ALDH1A1NPSR1MEN1KMT2AKDM4E | |
| SCHEMBL10553212 | 0.74 | NPSR1 (0.36) | ALDH1A1CYP2D6SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL28118734 | 0.73 | CYP2D6 (0.46) | ALDH1A1CYP2D6SMN1; SMN2NPSR1MEN1 | |
| SCHEMBL10991852 | 0.73 | KMT2A (0.52) | ALDH1A1NPSR1MEN1KMT2AKDM4E | |
| SCHEMBL9658898 | 0.71 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140673-A | REACTING 4-AMINO-PIPERIDINES WITH ENOLIC ETHERS | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |