Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | HTR5A | P47898 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13344276 | 0.82 | CYP3A4 (0.39) | ADRA2AMETAP1SMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL22271488 | 0.82 | ADRA2A (0.39) | ADRA2AMETAP1SMN1; SMN2CYP3A4TDP1 | |
| Methyl Alcohol SCHEMBL28381336 | 0.80 | ADRA2A (0.38) | ADRA2AMETAP1SMN1; SMN2CYP3A4TDP1 | |
| Methane SCHEMBL27200271 | 0.80 | ADRA2A (0.38) | ADRA2AMETAP1SMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL20994730 | 0.79 | ADRA2A (0.40) | ADRA2AMETAP1SMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL27710352 | 0.79 | ADRA2A (0.37) | ADRA2AMETAP1SMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL11532437 | 0.79 | LMNA (0.38) | ADRA2AMETAP1SMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL20255376 | 0.78 | ADRA2A (0.35) | ADRA2AMETAP1CYP3A4HTR5AALDH1A1 | |
| SCHEMBL245744 | 0.77 | ADRA2A (0.36) | ADRA2AMETAP1SMN1; SMN2CYP3A4TDP1 | |
| SCHEMBL15869741 | 0.77 | ALDH1A1 (0.35) | ADRA2AMETAP1SMN1; SMN2CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |