Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529393 | 0.76 | HTR1A (0.37) | TP53HTTLMNAALDH1A1CYP1A2 | |
| SCHEMBL3567261 | 0.72 | P2RX7 (0.45) | ALDH1A1CYP1A2MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11529183 | 0.70 | ALDH1A1 (0.49) | KDM4EHTTLMNAALDH1A1HSD17B10 | |
| SCHEMBL11530272 | 0.69 | POLB (0.49) | KDM4EHTTLMNAALDH1A1HSD17B10 | |
| SCHEMBL11529414 | 0.68 | SMN1; SMN2 (0.48) | TP53KDM4EHTTLMNAALDH1A1 | |
| SCHEMBL27196361 | 0.68 | GSK3B (0.51) | KDM4EHTTLMNAALDH1A1CYP1A2 | |
| SCHEMBL29852720 | 0.67 | CA12 (0.36) | KDM4EKCNH2S1PR1S1PR3LMNA | |
| SCHEMBL11528581 | 0.66 | CYP1A2 (0.38) | KDM4EHTTLMNAALDH1A1CYP1A2 | |
| SCHEMBL11529854 | 0.65 | CYP2C9 (0.42) | TP53KDM4ELMNAALDH1A1CYP1A2 | |
| SCHEMBL3405792 | 0.65 | HTT (0.43) | HTTLMNAALDH1A1CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144339-A | TREATMENT OF BILHARZIASIS | RHONE-POULENC INDUSTRIES (FR) | 1979-03-13 | — | — | US | disclosed |
| US-4138487-A | NEMATOCIDES | RHONE-POULENC INDUSTRIES (FR) | 1979-02-06 | — | — | US | disclosed |
| US-4110450-A | BILHARZIASIS | RHONE-POULENC INDUSTRIES (FR) | 1978-08-29 | — | — | US | disclosed |