SCHEMBL11530906

SCHEMBL11530906

CCCCCC(=O)N(CCC)c1nc(C)co1

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PLA2G4A P47712 1/20 0.33
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11531155 0.96 ALDH1A1 (0.36) MAPT
SCHEMBL11529943 0.94 ELANE (0.36)
SCHEMBL11528881 0.93 KDM5A (0.36) PLA2G4A
SCHEMBL11533686 0.90 PLA2G4A (0.33) PLA2G4A
SCHEMBL11528434 0.90 ELANE (0.36)
SCHEMBL11531654 0.89 TP53 (0.38)
SCHEMBL11533073 0.89 GPR84 (0.41) MAPT
SCHEMBL11531229 0.87 MLYCD (0.40)
SCHEMBL11534629 0.85 MLYCD (0.35)
SCHEMBL11533525 0.85 ALDH1A1 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4150143-A N-Substituted-acylamino-oxazoles as antiasthma agents LILLY INDUSTRIES LIMITED (GB) 1979-04-17 US disclosed
US-4143047-A 2-SULFINYL AND 2-SULFONYL OXAZOLES LILLY INDUSTRIES LIMITED (GB) 1979-03-06 US disclosed
US-4122183-A ANTIASTHMATIC LILLY INDUSTRIES LIMITED (GB) 1978-10-24 US disclosed