Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.34 |
| ▸ | CA2 | P00918 | 5/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 7/20 | 0.34 |
| ▸ | SCN1A | P35498 | 6/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 6/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422589 | 0.78 | LRRK2 (0.45) | CA1CA2CA9ALDH1A1SNCA | |
| SCHEMBL11532165 | 0.69 | LRRK2 (0.41) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL11315254 | 0.68 | LRRK2 (0.41) | CA1CA2CA9ALDH1A1KMT2A | |
| SCHEMBL10586071 | 0.66 | TIMP3 (0.44) | ALDH1A1POLBSNCAMEN1KMT2A | |
| SCHEMBL11716215 | 0.64 | CA2 (0.49) | CA1CA2CA9ALDH1A1KMT2A | |
| SCHEMBL11721290 | 0.64 | CA2 (0.71) | CA1CA2CA5ACA7CA5B | |
| SCHEMBL149505 | 0.63 | CA1 (0.74) | CA1CA2CA9ALDH1A1MEN1 | |
| SCHEMBL10585378 | 0.63 | TIMP3 (0.35) | ALDH1A1SNCAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL27729129 | 0.62 | CA1 (0.72) | CA1CA2CA9ALDH1A1MEN1 | |
| SCHEMBL11516706 | 0.62 | CA2 (0.45) | CA1CA2CA9ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141890-A | FIBER-REACTIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | claimed |
| US-4092308-A | 4-Sulphomethyl substituted hydroxypyridone azo dyestuffs | CIBA-GEIGY CORPORATION (US) | 1978-05-30 | — | — | US | claimed |