Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | GAPDH | P04406 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534203 | 0.76 | MEN1 (0.45) | POLBTDP1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11533101 | 0.72 | KMT2A (0.40) | POLBKMT2AGAAMEN1MAPT | |
| SCHEMBL11533430 | 0.71 | HPGD (0.40) | ALDH1A1HPGDL3MBTL1HTTNPSR1 | |
| SCHEMBL11569730 | 0.71 | ALDH1A1 (0.37) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL8833289 | 0.68 | SMN1; SMN2 (0.66) | POLBTDP1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL11664943 | 0.66 | NPC1 (0.31) | ALDH1A1HTT | |
| SCHEMBL2322149 | 0.63 | SMN1; SMN2 (0.59) | POLBTDP1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL9041665 | 0.63 | SMN1; SMN2 (0.52) | KMT2ALMNASMN1; SMN2GAAMEN1 | |
| SCHEMBL172042 | 0.63 | MAPT (0.65) | KMT2AGAPDHSMN1; SMN2GAAMEN1 | |
| SCHEMBL11539690 | 0.62 | KMT2A (0.49) | POLBKMT2AGAPDHLMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092325-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1978-05-30 | — | — | US | claimed |
| US-4134900-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4134896-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4098794-A | N-Thiazolyl-5,6-dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides | WARNER-LAMBERT COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4097441-A | 5,6-Dihydro-4-oxo-4H-thieno 2,3-b!thiopyran-5-carboxamides | WARNER-LAMBERT COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4092325-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1978-05-30 | — | — | US | disclosed |