Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533430 | 0.87 | HPGD (0.40) | ALDH1A1HTTNPC1PPARGRAB9A | |
| SCHEMBL11533101 | 0.81 | KMT2A (0.40) | ALDH1A1HTTNPC1PPARGRAB9A | |
| SCHEMBL11534203 | 0.76 | MEN1 (0.45) | ALDH1A1HTTNPC1RAB9AMEN1 | |
| SCHEMBL11664943 | 0.72 | NPC1 (0.31) | ALDH1A1HTTNPC1PPARGRAB9A | |
| SCHEMBL28808246 | 0.71 | ALDH1A1 (0.36) | ALDH1A1HTTNPC1PPARGRAB9A | |
| SCHEMBL11535382 | 0.71 | POLB (0.44) | ALDH1A1HTTHPGDMEN1MAPT | |
| SCHEMBL4573400 | 0.69 | ALDH1A1 (0.32) | ALDH1A1HTTNPC1PPARGRAB9A | |
| SCHEMBL11619177 | 0.67 | NPC1 (0.32) | ALDH1A1HTTNPC1PPARGRAB9A | |
| Hydrochloric Acid SCHEMBL7290256 | 0.66 | METAP1 (0.46) | — | |
| SCHEMBL5311960 | 0.60 | KMT2A (0.55) | RAB9AMEN1MAPTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134896-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4134896-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4134896-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4134900-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4134900-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4098794-A | N-Thiazolyl-5,6-dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides | WARNER-LAMBERT COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4098794-A | N-Thiazolyl-5,6-dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides | WARNER-LAMBERT COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4097441-A | 5,6-Dihydro-4-oxo-4H-thieno 2,3-b!thiopyran-5-carboxamides | WARNER-LAMBERT COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4097441-A | 5,6-Dihydro-4-oxo-4H-thieno 2,3-b!thiopyran-5-carboxamides | WARNER-LAMBERT COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4097441-A | 5,6-Dihydro-4-oxo-4H-thieno 2,3-b!thiopyran-5-carboxamides | WARNER-LAMBERT COMPANY (US) | 1978-06-27 | — | — | US | disclosed |
| US-4092325-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1978-05-30 | — | — | US | disclosed |
| US-4092325-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1978-05-30 | — | — | US | disclosed |
| US-4092325-A | 5,6-Dihydro-4-oxo-4H-thieno[2,3-b]thiopyran-5-carboxamides, and process for the preparation thereof | WARNER-LAMBERT COMPANY (US) | 1978-05-30 | — | — | US | disclosed |