Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.32 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.31 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10970398 | 0.89 | CYP2C9 (0.39) | CYP2C9DPP7DPP8DPP9MEN1 | |
| SCHEMBL11535880 | 0.81 | SIRT6 (0.39) | DPP7DPP8DPP9DPP4CPB2 | |
| SCHEMBL11539434 | 0.73 | CPB2 (0.45) | DPP7DPP8DPP9CYP1A2CPB2 | |
| SCHEMBL10967630 | 0.73 | GABRR1 (0.31) | — | |
| SCHEMBL3455673 | 0.73 | SLC6A5 (0.54) | SLC6A5 | |
| SCHEMBL4184576 | 0.73 | SLC6A5 (0.54) | SLC6A5 | |
| SCHEMBL4184574 | 0.73 | SLC6A5 (0.54) | SLC6A5 | |
| SCHEMBL23168117 | 0.71 | DPP7 (0.39) | CYP2C9DPP7DPP8DPP9DPP4 | |
| SCHEMBL22342420 | 0.71 | CTSK (0.44) | CYP2C9DPP7DPP8DPP9DPP4 | |
| SCHEMBL11511932 | 0.70 | CYP2C9 (0.36) | CYP2C9DPP7DPP8DPP9DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134918-A | ENZYME INHIBITORS, ANTIBODY INHIBITORS | MERRELL TORAUDE ET COMPAGNIE (FR) | 1979-01-16 | — | — | US | disclosed |