Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | TSHR | P16473 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.73 |
| ▸ | HTR1A | P08908 | 4/20 | 0.67 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.67 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.67 |
| ▸ | HTR1D | P28221 | 1/20 | 0.62 |
| ▸ | HTR1B | P28222 | 1/20 | 0.62 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | DRD1 | P21728 | 1/20 | 0.59 |
| ▸ | DRD4 | P21917 | 1/20 | 0.59 |
| ▸ | DRD3 | P35462 | 1/20 | 0.59 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12603046 | 0.83 | ALDH1A1 (0.79) | ALDH1A1HSD17B10TSHRL3MBTL1HTR1A | |
| SCHEMBL7409161 | 0.81 | HTR1A (0.65) | ALDH1A1HSD17B10HTR1AADRA1DADRA1A | |
| SCHEMBL516162 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HSD17B10L3MBTL1HTR1AADRA1D | |
| SCHEMBL30960126 | 0.81 | ALDH1A1 (0.62) | ALDH1A1HSD17B10L3MBTL1HTR1AADRA1D | |
| SCHEMBL8584543 | 0.80 | HTR1A (0.63) | ALDH1A1HSD17B10HTR1AADRA1DADRA1A | |
| SCHEMBL13082245 | 0.80 | ADRB2 (0.64) | HTR1AADRA1DADRA1AADRA1BADRB2 | |
| SCHEMBL8585578 | 0.80 | HTR1A (0.58) | ALDH1A1HSD17B10TSHRL3MBTL1HTR1A | |
| SCHEMBL5825340 | 0.80 | ALDH1A1 (0.65) | ALDH1A1HSD17B10L3MBTL1MTNR1AMTNR1B | |
| SCHEMBL12804709 | 0.79 | HTR1D (0.62) | ALDH1A1HSD17B10TSHRL3MBTL1HTR1D | |
| Hydrochloric Acid SCHEMBL8053943 | 0.79 | DRD2 (0.71) | ALDH1A1HSD17B10HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152438-A | HYPOTENSIVE AGENTS | BEIERSDORF AKTIENGESELLSCHAFT (DE) | 1979-05-01 | — | — | US | disclosed |