Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.65 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.65 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | DRD2 | P14416 | 3/20 | 0.55 |
| ▸ | DRD4 | P21917 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 2/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.54 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601409 | 0.93 | KDM4E (0.64) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| Hydrochloric Acid SCHEMBL8053943 | 0.84 | DRD2 (0.71) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| Hydrochloric Acid SCHEMBL8584282 | 0.84 | HTR1A (0.61) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| 1-Methoxy-2-Butoxybenzene SCHEMBL31085542 | 0.84 | L3MBTL1 (0.63) | ALDH1A1HSD17B10MTNR1AMTNR1B | |
| 1-Methoxy-2-Butoxybenzene SCHEMBL364856 | 0.84 | L3MBTL1 (0.63) | ALDH1A1HSD17B10MTNR1AMTNR1B | |
| SCHEMBL7057420 | 0.83 | HTR1A (0.73) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| 1-Methoxy-2-Pentoxybenzene SCHEMBL15086389 | 0.82 | L3MBTL1 (0.67) | ALDH1A1HSD17B10 | |
| SCHEMBL11694746 | 0.81 | ADRB2 (0.67) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL11534872 | 0.81 | ALDH1A1 (0.79) | HTR1AADRA1DADRA1AADRA1BALDH1A1 | |
| Hydrochloric Acid SCHEMBL8055394 | 0.81 | HTR1A (0.71) | HTR1AADRA1DADRA1AADRA1BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4503067-A | HYPOTENSIVE, ANGINA PECTORIS | BOEHRINGER MANNHEIM GMBH (DE) | 1985-03-05 | — | — | US | disclosed |
| EP-0004920-B1 | DERIVATIVES OF CARBAZOLYL-4-OXYPROPANOLAMINE, METHODS FOR THEIR PREPARATION AND MEDICINES CONTAINING THEM | Roche Diagnostics GmbH (DE) | 1981-08-05 | — | — | EP | disclosed |
| EP-0004920-A1 | Derivatives of carbazolyl-4-oxypropanolamine, methods for their preparation and medicines containing them | Roche Diagnostics GmbH (DE) | 1979-10-31 | — | — | EP | disclosed |