Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11537204 | 0.81 | LTA4H (0.52) | ALDH1A1LTA4HPOLBDRD2HPGD | |
| SCHEMBL11539863 | 0.80 | OPRL1 (0.47) | MEN1KMT2ALTA4HOPRL1POLB | |
| SCHEMBL11638248 | 0.76 | ADRA1A (0.44) | ALDH1A1MEN1KMT2APOLBHPGD | |
| SCHEMBL11538594 | 0.72 | HTT (0.58) | ALDH1A1LTA4HPOLBDRD2HPGD | |
| SCHEMBL10760411 | 0.69 | OPRM1 (0.66) | ALDH1A1MEN1KMT2AOPRL1HSD11B1 | |
| SCHEMBL12702280 | 0.68 | MEN1 (0.76) | ALDH1A1MEN1KMT2AOPRL1HSD11B1 | |
| SCHEMBL11612235 | 0.67 | MEN1 (0.50) | ALDH1A1MEN1KMT2AOPRL1HSD11B1 | |
| SCHEMBL6097642 | 0.67 | ADRA1A (0.45) | MEN1KMT2ADRD3 | |
| SCHEMBL9301424 | 0.67 | ADRA1A (0.45) | MEN1KMT2AEPHX2 | |
| SCHEMBL795975 | 0.67 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AOPRL1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140781-A | Analgesic and neuraleptic 2-piperidinoalkyl-1,4-benzodioxans | CIBA-GEIGY CORPORATION (US) | 1979-02-20 | — | — | US | disclosed |
| US-4129655-A | Neuroleptic 2-piperidinoalkyl-1,4-benzodioxans | CIBA-GEIGY CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |
| US-4104396-A | NEUROLEPTIC, ANALGESIC | CIBA-GEIGY CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |