Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9302190 | 0.90 | MGLL (0.45) | ADRA1AADRA1DADRA1BCYP2D6CYP2C19 | |
| SCHEMBL9302364 | 0.89 | EPHX2 (0.46) | ADRA1AEPHX2TP53CYP1A2CYP3A4 | |
| SCHEMBL9301904 | 0.87 | ADRA1A (0.51) | ADRA1AADRA1DADRA1BTP53CYP1A2 | |
| SCHEMBL9301407 | 0.81 | ADRA1D (0.68) | ADRA1AADRA1DADRA1BSMN1; SMN2 | |
| SCHEMBL9302494 | 0.77 | ADRA1A (0.49) | ADRA1AADRA1DADRA1BTP53CYP1A2 | |
| SCHEMBL9301300 | 0.74 | ADRA1D (0.60) | ADRA1AADRA1DADRA1B | |
| SCHEMBL9302459 | 0.73 | CXCR4 (0.54) | ADRA1AADRA1DADRA1BHDAC8TP53 | |
| SCHEMBL9302003 | 0.73 | ADRA1D (0.60) | ADRA1AADRA1DADRA1BTSHRSMN1; SMN2 | |
| SCHEMBL9301418 | 0.73 | ACHE (0.43) | EPHX1EPHX2CYP2C19MEN1KMT2A | |
| SCHEMBL9301885 | 0.73 | CXCR4 (0.56) | ADRA1ATP53CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | claimed |
| US-5286735-A | Antidepressants, anxiolytic agents | PIERRE FABRE MEDICAMENT (FR) | 1994-02-15 | — | — | US | disclosed |