Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SOD1 | P00441 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533246 | 0.79 | KIF11 (0.40) | KMT2AL3MBTL1MAPTSOD1MEN1 | |
| SCHEMBL11540051 | 0.77 | ALDH1A1 (0.40) | KMT2AL3MBTL1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL11536704 | 0.74 | RORC (0.41) | LMNAALDH1A1 | |
| SCHEMBL11539449 | 0.74 | KMT2A (0.41) | KMT2AL3MBTL1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL11536087 | 0.74 | KMT2A (0.50) | KMT2AL3MBTL1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL11536812 | 0.73 | ALDH1A1 (0.42) | KMT2ASOD1MEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL11535177 | 0.73 | KCNN4 (0.42) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11535988 | 0.72 | TSHR (0.38) | KMT2AL3MBTL1MAPTMEN1SMN1; SMN2 | |
| SCHEMBL10211503 | 0.72 | L3MBTL1 (0.57) | KMT2AL3MBTL1MAPTSOD1SMN1; SMN2 | |
| SCHEMBL11537656 | 0.71 | KMT2A (0.41) | KMT2AL3MBTL1MAPTMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139625-A | 5-(Substituted triphenylmethyl)picolinamides and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-02-13 | — | — | US | disclosed |
| US-4133887-A | Trityl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |
| US-4127662-A | ANTIACNE | SCHERING CORPORATION (US) | 1978-11-28 | — | — | US | disclosed |
| US-4123433-A | ANTIACNE AGENTS | SCHERING CORPORATION (US) | 1978-10-31 | — | — | US | disclosed |
| US-4044140-A | Trityl picolinic acid derivatives and their use as anti-acne agents | SCHERING CORPORATION (US) | 1977-08-23 | — | — | US | disclosed |