Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PLEC | Q15149 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3800105 | 0.81 | MAPT (0.55) | MAPTSMN1; SMN2ADAMTS4HPGDRAB9A | |
| SCHEMBL3098750 | 0.81 | ALDH1A1 (0.53) | MAPTSMN1; SMN2L3MBTL1ADAMTS4HPGD | |
| SCHEMBL9517508 | 0.81 | MAPT (0.59) | MAPTSMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL28344398 | 0.80 | RAB9A (0.53) | MAPTSMN1; SMN2HPGDRAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL9537225 | 0.80 | MAPT (0.53) | MAPTSMN1; SMN2ADAMTS4HPGDRAB9A | |
| Hydrochloric Acid SCHEMBL6619824 | 0.80 | ALDH1A1 (0.51) | MAPTSMN1; SMN2L3MBTL1ADAMTS4HPGD | |
| Hydrochloric Acid SCHEMBL29064766 | 0.80 | ALDH1A1 (0.51) | MAPTSMN1; SMN2L3MBTL1ADAMTS4HPGD | |
| SCHEMBL3781170 | 0.80 | MKNK1 (0.53) | MAPTL3MBTL1ADAMTS4ALDH1A1HSD17B10 | |
| SCHEMBL8085526 | 0.79 | L3MBTL1 (0.49) | MAPTSMN1; SMN2L3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL28211105 | 0.79 | MAPT (0.44) | MAPTSMN1; SMN2L3MBTL1ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4142054-A | TRIVALENT THALLIUM SALT | THE UPJOHN COMPANY (US) | 1979-02-27 | — | — | US | disclosed |
| US-4135051-A | ENOL ETHER OF AN ARYL ALKYL KETONE WITH A THALLIJM SALT, REGENERATION OF THALLIUM SALT BY ADDING PERACID AND REACTIVE METAL COMPOUND | THE UPJOHN COMPANY (US) | 1979-01-16 | — | — | US | disclosed |
| US-4107439-A | Process for preparing arylalkanoic acid derivatives | THE UPJOHN COMPANY (US) | 1978-08-15 | — | — | US | disclosed |