Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.53 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.49 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 2/20 | 0.47 |
| ▸ | IKBKB | O14920 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3098750 | 0.87 | ALDH1A1 (0.53) | HSD17B10L3MBTL1POLBMAPTTDP1 | |
| SCHEMBL3790168 | 0.85 | PARP10 (0.47) | MKNK1CHEK2MKNK2HSD17B10TDP1 | |
| Hydrochloric Acid SCHEMBL29064766 | 0.85 | ALDH1A1 (0.51) | HSD17B10L3MBTL1POLBMAPTTDP1 | |
| Hydrochloric Acid SCHEMBL6619824 | 0.85 | ALDH1A1 (0.51) | HSD17B10L3MBTL1POLBMAPTTDP1 | |
| SCHEMBL3788399 | 0.85 | CHEK2 (0.53) | MKNK1CHEK2MKNK2BCAT2HSD17B10 | |
| SCHEMBL2026663 | 0.85 | L3MBTL1 (0.52) | MKNK1CHEK2MKNK2BCAT2HSD17B10 | |
| SCHEMBL30903715 | 0.85 | L3MBTL1 (0.52) | MKNK1CHEK2MKNK2BCAT2HSD17B10 | |
| SCHEMBL3785246 | 0.84 | PARP1 (0.42) | MKNK1CHEK2MKNK2PARP1MAP4K4 | |
| SCHEMBL25365029 | 0.84 | ADAMTS4 (0.48) | MKNK1CHEK2BCAT2HSD17B10POLB | |
| SCHEMBL3800105 | 0.84 | MAPT (0.55) | HSD17B10MAPTALDH1A1ADAMTS4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | MKNK1 3527/4885CHEK2 1019/4885MKNK2 2702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.