Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 6/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542228 | 0.86 | KDM4E (0.54) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 | |
| Acetone SCHEMBL27408651 | 0.82 | OPRD1 (0.45) | SLC6A2SLC6A3SLC6A4KDM4ECYP2D6 | |
| SCHEMBL11542902 | 0.82 | IDO1 (0.61) | SLC6A3L3MBTL1MEN1KMT2AKDM4E | |
| SCHEMBL11539312 | 0.82 | PKM (0.49) | L3MBTL1KMT2AKDM4ETSHR | |
| SCHEMBL11374864 | 0.78 | MEN1 (0.56) | SLC6A2SLC6A3SLC6A4HTR1AL3MBTL1 | |
| SCHEMBL24322808 | 0.73 | L3MBTL1 (0.77) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 | |
| SCHEMBL11377141 | 0.73 | LTA4H (0.46) | SLC6A2SLC6A3SLC6A4HTR1AL3MBTL1 | |
| SCHEMBL5878421 | 0.73 | L3MBTL1 (0.77) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 | |
| SCHEMBL3315836 | 0.72 | SLC6A4 (0.39) | SLC6A2SLC6A3SLC6A4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11552618 | 0.71 | TSHR (0.50) | L3MBTL1MEN1KMT2AKDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4170653-A | Antidepressant naphthyloxy piperidino and pyrrolidino propanol ethers | Ayerst McKenna and Harrison Limited (CA) | 1979-10-09 | — | — | US | disclosed |
| US-4060613-A | ANTIDEPRESSANT | AYERST MCKENNA AND HARRISON LTD. (CA) | 1977-11-29 | — | — | US | disclosed |