Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4097244 | 0.83 | MMP1 (0.47) | NPC1RAB9AALDH1A1POLBMMP1 | |
| SCHEMBL9875296 | 0.81 | CRHBP (0.60) | CRHBPCRHR2PKMESR1ESR2 | |
| SCHEMBL6715200 | 0.78 | BCHE (0.42) | NPC1RAB9APKMALDH1A1POLB | |
| SCHEMBL2971231 | 0.78 | MMP1 (0.44) | NPC1RAB9AALDH1A1POLBMMP1 | |
| SCHEMBL27603109 | 0.77 | TRPM8 (0.47) | NPC1RAB9APKMALDH1A1POLB | |
| SCHEMBL8181001 | 0.75 | SMN1; SMN2 (0.50) | NPC1RAB9AALDH1A1MMP1MMP2 | |
| SCHEMBL27821076 | 0.74 | CRHBP (0.57) | CRHBPCRHR2PKMESR1ESR2 | |
| SCHEMBL28553963 | 0.74 | CRHBP (0.57) | CRHBPCRHR2PKMESR1ESR2 | |
| SCHEMBL11458475 | 0.74 | CRHBP (0.51) | CRHBPCRHR2NPC1RAB9APKM | |
| SCHEMBL7127285 | 0.73 | MMP1 (0.43) | NPC1RAB9AALDH1A1POLBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150223-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1979-04-17 | — | — | US | disclosed |
| US-4032521-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1977-06-28 | — | — | US | disclosed |