SCHEMBL6715200

SCHEMBL6715200

CC(CC(=O)Oc1cccs1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.42
PKM P14618 1/20 0.42
POLB P06746 2/20 0.41
LTB4R Q15722 1/20 0.41
LTB4R2 Q9NPC1 1/20 0.41
HPGD P15428 3/20 0.41
ALDH1A1 P00352 2/20 0.41
TSHR P16473 1/20 0.41
FFAR1 O14842 2/20 0.40
RAB9A P51151 3/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C19 P33261 1/20 0.40
NPC1 O15118 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TRPM8 Q7Z2W7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27603109 0.84 TRPM8 (0.47) PKMPOLBALDH1A1RAB9ACYP2C19
SCHEMBL1756467 0.81 RAB9A (0.44) POLBHPGDALDH1A1TSHRRAB9A
SCHEMBL1756479 0.81 RAB9A (0.44) POLBHPGDALDH1A1TSHRRAB9A
SCHEMBL3421330 0.80 RAB9A (0.42) POLBHPGDALDH1A1RAB9ACYP3A4
SCHEMBL2679583 0.79 ELANE (0.47) HPGDALDH1A1TSHRFFAR1RAB9A
SCHEMBL11540433 0.78 CRHBP (0.45) PKMPOLBHPGDALDH1A1TSHR
SCHEMBL9794842 0.78 ALDH1A1 (0.50) BCHEPOLBLTB4RLTB4R2HPGD
SCHEMBL4097244 0.77 MMP1 (0.47) POLBHPGDALDH1A1TSHRRAB9A
SCHEMBL8818944 0.77 HPGD (0.47) BCHEPKMPOLBHPGDALDH1A1
SCHEMBL8202887 0.77 HPGD (0.47) BCHEPKMPOLBHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1109551-A4 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES COMPETITIVE TECH INC (US) 2004-10-20 EP disclosed
EP-1109551-A1 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES Competitive Technologies, Inc. (US) 2001-06-27 EP disclosed
WO-2000010564-A1 4-AMINO-3-MERCAPTO-1,2,4-TRIAZOLES COMPETITIVE TECHNOLOGIES, INC. (US) 2000-03-02 WO disclosed