Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylformamide SCHEMBL133174 | 0.85 | LMNA (0.55) | LMNA | |
| Butane SCHEMBL3144035 | 0.82 | LMNA (0.50) | LMNA | |
| Dimethylformamide SCHEMBL314310 | 0.81 | LMNA (0.60) | LMNA | |
| Butane SCHEMBL2557609 | 0.78 | LMNA (0.63) | LMNA | |
| Butane SCHEMBL818136 | 0.78 | LMNA (0.63) | LMNA | |
| Butane SCHEMBL10830357 | 0.78 | LMNA (0.50) | LMNA | |
| SCHEMBL7995654 | 0.77 | LMNA (0.55) | LMNA | |
| SCHEMBL1975022 | 0.77 | USP2 (0.32) | — | |
| Dimethylformamide SCHEMBL131192 | 0.77 | LMNA (0.55) | LMNA | |
| Propionaldehyde SCHEMBL8906570 | 0.76 | LMNA (0.60) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175087-A | ENAMINOKETONES WITH ALKYLLITHIUM | ELI LILLY AND COMPANY (US) | 1979-11-20 | — | — | US | disclosed |