Butane

Butane

SCHEMBL3144035

CCCC.CCN(C=O)CC.CCOC(C)OCC

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7995654 0.96 LMNA (0.55) LMNA
Butane SCHEMBL3137845 0.86 LMNA (0.48) LMNA
Dimethylformamide SCHEMBL133174 0.83 LMNA (0.55) LMNA
Butane SCHEMBL11523278 0.82 LMNA (0.44) LMNA
Butane SCHEMBL11540528 0.82 LMNA (0.48) LMNA
Butane SCHEMBL11344980 0.81 LMNA (0.43) LMNA
Butane SCHEMBL2557609 0.80 LMNA (0.63) LMNA
Butane SCHEMBL818136 0.80 LMNA (0.63) LMNA
Butane SCHEMBL10830357 0.79 LMNA (0.50) LMNA
Butane SCHEMBL8312214 0.78 LMNA (0.60) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4206205-B1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND PRIMEGENE BEIJING CO LTD (CN) 2026-03-04 EP claimed
US-20230303578-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND PRIMEGENE (BEIJING) CO., LTD. (CN) 2023-09-28 US claimed
EP-4206205-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND Primegene (Beijing) Co., Ltd. (CN) 2023-07-05 EP claimed
WO-2022042577-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND 北京普祺医药科技有限公司 2022-03-03 WO claimed
CN-103030598-B The preparation method of methoxy acrylic bactericide SHANGHAI HEBEN PHARMACEUTICAL CO., LTD. (CN) 2016-04-13 CN claimed
CN-103626691-B The preparation method of ZEN 90160 Shanghai Heben-Eastsun Medicaments Co., Ltd. (CN) 2015-10-21 CN claimed
CN-104151233-A Preparation method of agricultural bactericide ZHEJIANG TIDE CROP TECHNOLOGY CO LTD 2014-11-19 CN claimed
CN-103626691-A Picoxystrobin preparation method SHANGHAI HEBEN EASTSUN MEDICAMENTS CO LTD 2014-03-12 CN claimed
CN-103030598-A Method for preparing strobilurin fungicide SHANGHAI HEBEN EASTSUN MEDICAMENTS CO LTD 2013-04-10 CN claimed
EP-4206205-B1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND PRIMEGENE BEIJING CO LTD (CN) 2026-03-04 EP disclosed
WO-2025047698-A1 PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, METHOD FOR PRODUCING SAME, LIQUID CRYSTAL DEVICE, SEMICONDUCTOR DEVICE, POLYMER, AND COMPOUND JSR株式会社 2025-03-06 WO disclosed
US-20230303578-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND PRIMEGENE (BEIJING) CO., LTD. (CN) 2023-09-28 US disclosed
EP-4206205-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND Primegene (Beijing) Co., Ltd. (CN) 2023-07-05 EP disclosed
WO-2022042577-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND 北京普祺医药科技有限公司 2022-03-03 WO disclosed
US-4559347-A 3-Substituted-5-alkyl-1,6-naphthyridin-2(1H)-ones, cardiotonic use and preparation thereof STERLING DRUG INC. (US) 1985-12-17 US disclosed
EP-0163599-A2 Pyrimidopyrimidine derivatives, processes for producing them, pharmaceutical compositions containing them and their use as anti-allergic agents NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) 1985-12-04 EP disclosed
US-4517190-A 5-Alkyl-1,6-naphthyridin-2(1H)-ones and cardiotonic use thereof STERLING DRUG INC. (US) 1985-05-14 US disclosed
EP-0101952-A1 5-Alkyl-1,6-naphthyridin-2(1H)-ones, intermediates, their preparation and their cardiotonic use STERLING DRUG INC. (US) 1984-03-07 EP disclosed
US-4415580-A Certain 2-(1H)-pyridinones cardiotonic compositions containing same and method of using same STERLING DRUG INC. (US) 1983-11-15 US disclosed
US-4175087-A ENAMINOKETONES WITH ALKYLLITHIUM ELI LILLY AND COMPANY (US) 1979-11-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303578-A1 PREPARATION METHOD FOR PYRROLOPYRIMIDINE COMPOUND DPYD, RPLP2, DHPS LMNA 4225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.