SCHEMBL7995654

SCHEMBL7995654

CCN(C=O)CC.CCOC(C)OCC

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.55
THRB P10828 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL3144035 0.96 LMNA (0.50) LMNA
Dimethylformamide SCHEMBL314310 0.81 LMNA (0.60) LMNATHRB
Butane SCHEMBL3137845 0.81 LMNA (0.48) LMNA
SCHEMBL2035531 0.79
Butane SCHEMBL11523278 0.78 LMNA (0.44) LMNA
Acetaldehyde SCHEMBL212729 0.78 LMNA (0.71) LMNATHRB
SCHEMBL4293299 0.78 LMNA (0.71) LMNATHRB
Dimethylformamide SCHEMBL133174 0.77 LMNA (0.55) LMNATHRB
Dimethylformamide SCHEMBL131192 0.77 LMNA (0.55) LMNATHRB
SCHEMBL10844040 0.77 LMNA (0.55) LMNATHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3952007-A Processes for preparing 5-nitro-1-methyl-2-(2-dialkylaminovinyl)-imidazole and 5-nitro-1-methyl-2-imidazolyl carboxaldehyde SCHERING AKTIENGESELLSCHAFT (DT) 1976-04-20 US claimed
WO-2001017977-A1 1,3,5-TRIAZINES AS HERBICIDES NIHON BAYER AGROCHEM K.K. (JP) 2001-03-15 WO disclosed
EP-0089730-B1 GUANIDINO HETEROCYCLICPHENYLAMIDINES, PROCESSES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE ISTITUTO DE ANGELI S.p.A. (IT) 1987-05-27 EP disclosed
US-4645841-A ANTIULCER AGENTS ISTITUTO DE ANGELI, S.P.A. (IT) 1987-02-24 US disclosed
US-4548944-A ANTIULCER, ANTISECRETORY AGENTS ISTITUTO DE ANGELI S.P.A. (IT) 1985-10-22 US disclosed
EP-0089730-A2 Guanidino heterocyclicphenylamidines, processes for their preparation and their pharmaceutical use ISTITUTO DE ANGELI S.p.A. (IT) 1983-09-28 EP disclosed
US-3952007-A Processes for preparing 5-nitro-1-methyl-2-(2-dialkylaminovinyl)-imidazole and 5-nitro-1-methyl-2-imidazolyl carboxaldehyde SCHERING AKTIENGESELLSCHAFT (DT) 1976-04-20 US disclosed