Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 8/20 | 0.42 |
| ▸ | MMP2 | P08253 | 6/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | MMP8 | P22894 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6790942 | 0.72 | CA12 (0.42) | CA12MMP2CA14CA1MMP8 | |
| SCHEMBL8336668 | 0.72 | CA12 (0.42) | CA12MMP2CA14CA1MMP8 | |
| SCHEMBL11766709 | 0.69 | MMP2 (0.39) | CA12MMP2CA14CA1MMP8 | |
| SCHEMBL336549 | 0.67 | TSHR (0.50) | CA12MMP2CA14CA1MMP8 | |
| SCHEMBL22590166 | 0.67 | CTSC (0.41) | CA12MMP2CA14CA2FDPS | |
| SCHEMBL3309690 | 0.67 | CA12 (0.42) | CA12MMP2CA14CA1MMP8 | |
| SCHEMBL10881526 | 0.67 | ALDH1A1 (0.45) | CA12MMP2CA14CA1MMP8 | |
| SCHEMBL11656666 | 0.67 | CYP2C9 (0.46) | CA12MMP2CA14CA1MMP8 | |
| SCHEMBL10718498 | 0.67 | CA12 (0.38) | CA12MMP2CA14CA1MMP8 | |
| SCHEMBL11776086 | 0.67 | L3MBTL1 (0.39) | CA12MMP2CA14CA1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150223-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1979-04-17 | — | — | US | disclosed |
| US-4032521-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1977-06-28 | — | — | US | disclosed |