Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.42 |
| ▸ | MMP2 | P08253 | 5/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ENO1 | P06733 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18161698 | 0.84 | ASAH1 (0.35) | CA12MMP2ENO1CA2ASAH1 | |
| SCHEMBL10718498 | 0.76 | CA12 (0.38) | CA12MMP2CA14ENO1CA2 | |
| SCHEMBL22590166 | 0.76 | CTSC (0.41) | CA12MMP2CA14ENO1CA2 | |
| SCHEMBL11656666 | 0.76 | CYP2C9 (0.46) | CA12MMP2CA14ENO1CA2 | |
| SCHEMBL4635288 | 0.73 | ALDH1A1 (0.37) | CA12MMP2CA14ENO1CA2 | |
| SCHEMBL18825531 | 0.71 | KDM4E (0.37) | CA12MMP2CA14 | |
| SCHEMBL1847963 | 0.71 | GAA (0.43) | CA12CA2ASAH1CA9CA1 | |
| SCHEMBL18825589 | 0.71 | CAMK2A (0.36) | CA12MMP2CA14ENO1CA2 | |
| SCHEMBL4633674 | 0.70 | LMNA (0.41) | CA12MMP2CA14 | |
| SCHEMBL18825533 | 0.70 | FAAH (0.34) | CA12MMP2CA14ENO1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828398-B2 | Compound for bone scanning and use thereof | TAIWAN HOPAX CHEMS. MFG. CO., LTD. (TW) | 2017-11-28 | — | — | US | disclosed |
| EP-3085390-A1 | COMPOUND FOR BONE SCANNING AND USE THEREOF | Taiwan Hopax Chems. Mfg. Co., Ltd. (TW) | 2016-10-26 | — | — | EP | disclosed |
| US-20160304545-A1 | COMPOUND FOR BONE SCANNING AND USE THEREOF | TAIWAN HOPAX CHEMS. MFG. CO., LTD. (TW) | 2016-10-20 | — | — | US | disclosed |
| US-8946144-B2 | Phosphonated glycopeptide and lipoglycopeptide antibiotics and uses thereof for the prevention and treatment of bone and joint infections | THE MEDICINES COMPANY (US) | 2015-02-03 | — | — | US | disclosed |
| US-20100113333-A1 | PHOSPHONATED GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | TARGANTA THERAPEUTICS, INC. (CA) | 2010-05-06 | — | — | US | disclosed |
| EP-2097440-A1 | PHOSPHONATED GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | Targanta Therapeutics Inc. (CA) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008077241-A1 | PHOSPHONATED GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | TARGANTA THERAPEUTICS, INC. (CA) | 2008-07-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304545-A1 | COMPOUND FOR BONE SCANNING AND USE THEREOF | SOST, BPGM, PPIP5K2 | CA12 2183/4885MMP2 2424/4885CA14 1418/4885 |
| US-20100113333-A1 | PHOSPHONATED GLYCOPEPTIDE AND LIPOGLYCOPEPTIDE ANTIBIOTICS AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | PGLS, BPGM, PAG1 | CA12 2457/4885MMP2 946/4885CA14 1693/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.