Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 1/20 | 0.48 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.48 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPPA | P01160 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544477 | 0.81 | TP53 (0.41) | KDM4EALDH1A1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL11542530 | 0.80 | ACSS2 (0.37) | CCNE2CCNE1CDK2ACSS2KDM4E | |
| SCHEMBL15086882 | 0.76 | HDAC1 (0.40) | KDM4EALDH1A1LMNANR4A2L3MBTL1 | |
| SCHEMBL11536828 | 0.75 | KDM4E (0.39) | CCNE2CCNE1CDK2ACSS2KDM4E | |
| SCHEMBL10533456 | 0.73 | — | — | |
| SCHEMBL6852449 | 0.73 | LMNA (0.38) | ACSS2LMNAKMT2AHDAC1 | |
| SCHEMBL15053076 | 0.73 | KDM4E (0.46) | KDM4EALDH1A1LMNANR4A2L3MBTL1 | |
| SCHEMBL15064334 | 0.72 | NLRP3 (0.54) | KDM4EALDH1A1LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL22313510 | 0.71 | HSD17B10 (0.34) | CCNE2CCNE1CDK2KDM4EALDH1A1 | |
| SCHEMBL16254887 | 0.71 | CCR4 (0.44) | KDM4EALDH1A1LMNANR4A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |