Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11536470 | 0.82 | CYP2C19 (0.44) | TP53ADORA1KDM4EHPGDADORA2A | |
| SCHEMBL11540720 | 0.81 | CCNE2 (0.48) | ADORA1KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11542530 | 0.76 | ACSS2 (0.37) | TP53KDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL11536828 | 0.74 | KDM4E (0.39) | TP53KDM4EMEN1KMT2AMAPT | |
| SCHEMBL11542179 | 0.73 | ALDH1A1 (0.47) | ADORA1HPGDADORA3ALDH1A1RAB9A | |
| SCHEMBL11544586 | 0.72 | LMNA (0.46) | HPGDALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL11538934 | 0.71 | LMNA (0.48) | HPGDALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28549890 | 0.70 | HSD11B1 (0.46) | TP53ADORA1KDM4EADORA2AADORA3 | |
| SCHEMBL28556119 | 0.70 | HSD11B1 (0.50) | TP53ADORA1ADORA2AADORA3ALDH1A1 | |
| SCHEMBL1527363 | 0.70 | LMNA (0.44) | ADORA1KDM4EHPGDALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4150143-A | N-Substituted-acylamino-oxazoles as antiasthma agents | LILLY INDUSTRIES LIMITED (GB) | 1979-04-17 | — | — | US | disclosed |
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |