Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6616831 | 0.79 | ALOX5 (0.40) | LMNAKMT2AGABRA1GABRB2FAAH | |
| SCHEMBL11541431 | 0.77 | TP53 (0.39) | LMNAKMT2ASMN1; SMN2CYP3A4HPGD | |
| SCHEMBL24704695 | 0.76 | KMT2A (0.36) | LMNAKMT2AGABRA1GABRB2SMN1; SMN2 | |
| SCHEMBL11542282 | 0.76 | ALDH1A1 (0.38) | KMT2ASMN1; SMN2POLBHPGDSLC6A2 | |
| SCHEMBL11514484 | 0.75 | LMNA (0.35) | LMNAKMT2AGABRA1GABRB2POLB | |
| SCHEMBL11543045 | 0.73 | PLK1 (0.49) | HPGDPTGS1SLC6A2L3MBTL1MAPT | |
| SCHEMBL26524850 | 0.73 | LMNA (0.33) | LMNAKMT2AGABRA1GABRB2SMN1; SMN2 | |
| SCHEMBL11548288 | 0.71 | ALDH1A1 (0.39) | LMNAKMT2ASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL11372476 | 0.71 | LMNA (0.42) | LMNAKMT2ASMN1; SMN2POLBCYP3A4 | |
| SCHEMBL11541466 | 0.70 | TSHR (0.38) | LMNAKMT2ASMN1; SMN2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4148799-A | Process for the preparation of 2-aryliminothiazoline solutions | BAYER AKTIENGESELLSCHAFT (DE) | 1979-04-10 | — | — | US | disclosed |