Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545485 | 0.92 | ADRB2 (0.51) | ADRB2ADRB1CYP1A2ADRB3ATM | |
| Tolamolol SCHEMBL611643 | 0.87 | ATM (0.59) | ADRB2ADRB1CYP1A2ADRB3ATM | |
| Tolamolol SCHEMBL613511 | 0.87 | ATM (0.59) | ADRB2ADRB1CYP1A2ADRB3ATM | |
| Tolamolol SCHEMBL8057907 | 0.86 | ATM (0.58) | ADRB2ADRB1CYP1A2ADRB3ATM | |
| SCHEMBL11545703 | 0.85 | ADRB1 (0.45) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL11543752 | 0.85 | ATM (0.55) | ADRB2ADRB1CYP1A2ADRB3ATM | |
| SCHEMBL10713962 | 0.85 | ADRB2 (0.56) | ADRB2ADRB1CYP1A2ADRB3ATM | |
| SCHEMBL11541226 | 0.83 | ADRB2 (0.64) | ADRB2ADRB1CYP1A2ADRB3ATM | |
| SCHEMBL11550848 | 0.83 | CYP3A4 (0.54) | ADRB2ADRB1CYP1A2ADRB3ATM | |
| SCHEMBL11544543 | 0.82 | CYP3A4 (0.58) | ADRB2ADRB1CYP1A2ADRB3ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4165384-A | ADRENERGIC BLOCKING AGENTS, CARDIOVASCULAR DISORDERS | AKTIEBOLAGET HASSLE (SE) | 1979-08-21 | — | — | US | disclosed |