Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.47 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936220 | 0.83 | RAB9A (0.63) | MEN1KMT2AHDAC6HPGDTSHR | |
| SCHEMBL11488532 | 0.81 | MEN1 (0.58) | MEN1KMT2APKMHDAC6HPGD | |
| SCHEMBL6764782 | 0.81 | ALDH1A1 (0.64) | HPGDTSHRALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL22747799 | 0.81 | HPGD (0.49) | MEN1KMT2AHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL578719 | 0.80 | LMNA (0.64) | MEN1KMT2APKMHPGDTSHR | |
| SCHEMBL11196941 | 0.79 | KMT2A (0.59) | MEN1KMT2APKMHPGDTSHR | |
| SCHEMBL9860833 | 0.78 | MEN1 (0.58) | MEN1KMT2APKMHPGDTSHR | |
| SCHEMBL4412374 | 0.76 | CYP1A2 (0.67) | MEN1KMT2ATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL3161189 | 0.75 | MEN1 (0.58) | MEN1KMT2APKMHPGDTSHR | |
| SCHEMBL3551990 | 0.75 | MEN1 (0.63) | MEN1KMT2APKMHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179439-A | Rifamycins and method for their preparation | INTREPRINDEREA DE ANTIBIOTICE IASI (RO) | 1979-12-18 | — | — | US | disclosed |