Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PTPRB | P23467 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11407183 | 0.82 | ALDH1A1 (0.70) | ALDH1A1LCKMEN1KMT2APOLB | |
| SCHEMBL11544341 | 0.79 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2RECQLCA5AMEN1 | |
| SCHEMBL11419316 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LCKSMN1; SMN2RECQLMAPT | |
| SCHEMBL11419363 | 0.78 | ALDH1A1 (0.50) | ALDH1A1LCKSMN1; SMN2RECQLMAPT | |
| SCHEMBL23469275 | 0.76 | ALDH1A1 (0.47) | ALDH1A1LCKSMN1; SMN2RECQLMEN1 | |
| SCHEMBL18183311 | 0.74 | ALDH1A1 (0.46) | ALDH1A1LCKSMN1; SMN2RECQLMEN1 | |
| SCHEMBL96185 | 0.74 | CA5A (0.52) | SMN1; SMN2FFAR4CA5AKMT2AMAPT | |
| SCHEMBL21056124 | 0.74 | POLB (0.59) | ALDH1A1SMN1; SMN2RECQLMEN1KMT2A | |
| SCHEMBL11408683 | 0.70 | RAPGEF4 (0.49) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL11416877 | 0.70 | HTT (0.63) | ALDH1A1LCKMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287441-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |