Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.64 |
| ▸ | MEN1 | O00255 | 9/20 | 0.64 |
| ▸ | RAB9A | P51151 | 8/20 | 0.63 |
| ▸ | NPC1 | O15118 | 8/20 | 0.63 |
| ▸ | MAPT | P10636 | 8/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.63 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547089 | 0.81 | KMT2A (0.51) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL4918597 | 0.78 | KMT2A (1.00) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL11544341 | 0.78 | ALDH1A1 (0.43) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL1719786 | 0.78 | RAB9A (1.00) | KMT2AMEN1RAB9ANPC1MAPT | |
| Hydrochloric Acid SCHEMBL8615399 | 0.76 | MEN1 (0.47) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL11543525 | 0.74 | JAK2 (0.39) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL28810823 | 0.73 | KMT2A (0.76) | KMT2AMEN1RAB9ANPC1MAPT | |
| Diphenylurea SCHEMBL133103 | 0.73 | SMN1; SMN2 (1.00) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL11545759 | 0.73 | SMN1; SMN2 (0.41) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL11007336 | 0.73 | KMT2A (0.70) | KMT2AMEN1RAB9ANPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145363-A | ANTIASTHMATICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1979-03-20 | — | — | US | disclosed |
| US-4063025-A | PROPHYLAXIS, ANTIASTHMATIC | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1977-12-13 | — | — | US | disclosed |