Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | FBP1 | P09467 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544037 | 0.86 | LMNA (0.46) | L3MBTL1TDP1MCL1MAPT | |
| SCHEMBL11547200 | 0.81 | MCL1 (0.43) | L3MBTL1TSHRALDH1A1MCL1GAA | |
| SCHEMBL8959611 | 0.75 | MCL1 (0.43) | L3MBTL1TSHRALDH1A1MCL1GAA | |
| SCHEMBL11548971 | 0.74 | L3MBTL1 (0.44) | L3MBTL1TDP1ESR2TSHRALDH1A1 | |
| SCHEMBL11548970 | 0.74 | L3MBTL1 (0.44) | L3MBTL1TDP1ESR2TSHRALDH1A1 | |
| SCHEMBL11545103 | 0.72 | KMT2A (0.49) | L3MBTL1TDP1ALDH1A1GAAHSD17B10 | |
| SCHEMBL29113502 | 0.71 | PTGER1 (0.45) | L3MBTL1TSHRALDH1A1MCL1GAA | |
| SCHEMBL10422274 | 0.70 | HSD17B10 (0.58) | L3MBTL1TDP1TSHRALDH1A1HPGD | |
| SCHEMBL6009063 | 0.70 | TSHR (0.55) | L3MBTL1TDP1TSHRALDH1A1MGAM | |
| SCHEMBL8973495 | 0.70 | L3MBTL1 (0.69) | L3MBTL1TDP1ESR2TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179513-A | Indole-2-carboxylic acids to effect CNS depressant activity | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4117129-A | INDOLOBENZOXAZEPINES AS CNS DEPRESSANTS | WARNER-LAMBERT COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-4066660-A | INTERMEDIATES IN THE PREPARATION OF INDOLOBENZOXAZEPINES | WARNER-LAMBERT COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-4013641-A | INDOLOBENZOXAZEPINES | XEROX CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |