Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | HTT | P42858 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | XIAP | P98170 | 1/20 | 0.58 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 2/20 | 0.54 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11546804 | 0.79 | KDM4E (0.62) | SMN1; SMN2ALDH1A1LMNAHTTTP53 | |
| SCHEMBL11548746 | 0.77 | PSMB8 (0.54) | SMN1; SMN2ALDH1A1LMNAHTTTP53 | |
| SCHEMBL10386027 | 0.77 | NLRP3 (0.51) | SMN1; SMN2ALDH1A1LMNAHTTTP53 | |
| SCHEMBL25735906 | 0.76 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1LMNAHTTTP53 | |
| SCHEMBL18460677 | 0.75 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1LMNAHTTTP53 | |
| SCHEMBL593172 | 0.74 | MAPT (0.74) | SMN1; SMN2ALDH1A1LMNAHTTTP53 | |
| SCHEMBL15474185 | 0.74 | XIAP (1.00) | SMN1; SMN2ALDH1A1LMNAHTTTP53 | |
| SCHEMBL27256654 | 0.73 | SMN1; SMN2 (0.64) | SMN1; SMN2ALDH1A1LMNAHTTTP53 | |
| SCHEMBL26280117 | 0.72 | SMN1; SMN2 (0.62) | SMN1; SMN2ALDH1A1LMNAHTTTP53 | |
| SCHEMBL1119999 | 0.72 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1LMNAHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |