Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.44 |
| ▸ | HPD | P32754 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545418 | 0.79 | SMN1; SMN2 (0.74) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10386822 | 0.79 | KDM4E (0.57) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11551548 | 0.79 | KDM4E (0.54) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL593172 | 0.72 | MAPT (0.74) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL20332043 | 0.71 | NOTUM (0.54) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17434593 | 0.70 | RORC (0.64) | KDM4EMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10386027 | 0.69 | NLRP3 (0.51) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11548746 | 0.69 | PSMB8 (0.54) | KDM4EMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL6205386 | 0.69 | HPD (0.58) | KDM4EMAPTALDH1A1KMT2ACYP1A2 | |
| SCHEMBL8752439 | 0.69 | MEN1 (0.66) | KDM4EMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4169091-A | Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-09-25 | — | — | US | disclosed |