Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | IKBKB | O14920 | 1/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014247 | 0.79 | LMNA (0.53) | ALDH1A1HPGDKDM4EGAARAB9A | |
| Urea SCHEMBL6014244 | 0.76 | ALDH1A1 (0.49) | ALDH1A1HPGDKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL8223252 | 0.74 | PTPN1 (0.44) | ALDH1A1HPGDKDM4EPI4K2ARAB9A | |
| SCHEMBL6014245 | 0.73 | TRPM8 (0.40) | ALDH1A1HPGDKDM4EGAAIKBKB | |
| SCHEMBL30682087 | 0.72 | KMT2A (0.46) | ALDH1A1HPGDKDM4EGAARAB9A | |
| SCHEMBL7668928 | 0.71 | MAPT (0.50) | ALDH1A1HPGDKDM4EGAAPI4K2A | |
| SCHEMBL8352155 | 0.70 | KDM4E (1.00) | ALDH1A1HPGDKDM4EGLAGAA | |
| Urea SCHEMBL6014279 | 0.69 | L3MBTL1 (0.42) | ALDH1A1HPGDKDM4EGAARAB9A | |
| SCHEMBL8756161 | 0.69 | KDM4E (0.54) | ALDH1A1HPGDKDM4EGLAGAA | |
| SCHEMBL30837 | 0.68 | IKBKB (1.00) | ALDH1A1HPGDKDM4EGLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134981-A | ANTIALLERGENS | PFIZER INC. (US) | 1979-01-16 | — | — | US | disclosed |
| US-4120962-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-4044134-A | FUSED WITH QUINOLINE OR PYRIDINE, 2-METHYL, ETHYL, OR ACETYL GROUP | PFIZER INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-3974161-A | Fused pyrimidin-4(3H)-ones as antiallergy agents | PFIZER INC. (US) | 1976-08-10 | — | — | US | disclosed |