Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014230 | 0.92 | NPC1 (0.39) | L3MBTL1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL6014246 | 0.88 | KMT2A (0.39) | L3MBTL1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL6014278 | 0.88 | KMT2A (0.39) | L3MBTL1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL6014311 | 0.87 | ALDH1A1 (0.39) | L3MBTL1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL6014269 | 0.82 | KMT2A (0.40) | L3MBTL1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL6014285 | 0.77 | TRPM8 (0.39) | L3MBTL1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL26617712 | 0.72 | KMT2A (0.46) | L3MBTL1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL30682087 | 0.72 | KMT2A (0.46) | L3MBTL1NPC1RAB9AALDH1A1HPGD | |
| Urea SCHEMBL6014301 | 0.69 | GABRA1 (0.42) | L3MBTL1NPC1RAB9AALDH1A1HPGD | |
| SCHEMBL11545648 | 0.69 | ALDH1A1 (0.54) | L3MBTL1NPC1RAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | claimed |
| WO-2006128268-A1 | UREIDIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THEIR USE ON THE TREATMENT OF INFLAMMATORY DISEASES | UNIVERSIDADE FEDERAL DO RIO DE JANEIRO - UFRJ (BR) | 2006-12-07 | — | — | WO | disclosed |