Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.51 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | GABRP | O00591 | 2/20 | 0.43 |
| ▸ | GABRD | O14764 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.43 |
| ▸ | GABRE | P78334 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11547197 | 0.87 | KMT2A (0.47) | ALDH1A1HSD17B10HPGDKDM4EPABPC1 | |
| SCHEMBL11548967 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HSD17B10HPGDKDM4EPABPC1 | |
| SCHEMBL12818486 | 0.78 | KDM4E (0.65) | ALDH1A1HSD17B10HPGDKDM4EPABPC1 | |
| SCHEMBL11544861 | 0.74 | MAPT (0.47) | ALDH1A1HSD17B10HPGDKDM4EKMT2A | |
| SCHEMBL11547919 | 0.73 | CYP1A2 (0.47) | ALDH1A1HPGDKDM4EKMT2APKM | |
| SCHEMBL4208219 | 0.73 | KDM4E (0.62) | ALDH1A1HSD17B10HPGDKDM4EPABPC1 | |
| SCHEMBL24482887 | 0.72 | ALDH1A1 (0.61) | ALDH1A1HSD17B10HPGDKDM4EPABPC1 | |
| SCHEMBL11529865 | 0.70 | KDM4E (1.00) | ALDH1A1HSD17B10HPGDKDM4EPABPC1 | |
| SCHEMBL11545106 | 0.70 | CCR2 (0.48) | ALDH1A1KDM4EKMT2APKMGAA | |
| SCHEMBL11547198 | 0.70 | TUBB4A (0.49) | ALDH1A1HSD17B10HPGDKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179513-A | Indole-2-carboxylic acids to effect CNS depressant activity | WARNER-LAMBERT COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4117129-A | INDOLOBENZOXAZEPINES AS CNS DEPRESSANTS | WARNER-LAMBERT COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-4066660-A | INTERMEDIATES IN THE PREPARATION OF INDOLOBENZOXAZEPINES | WARNER-LAMBERT COMPANY (US) | 1978-01-03 | — | — | US | disclosed |
| US-4013641-A | INDOLOBENZOXAZEPINES | XEROX CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |