SCHEMBL11547151

SCHEMBL11547151

Brc1c(C(Br)Br)cccc1C(Br)(Br)Br

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 1/20 0.36
ALDH1A1 P00352 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3376910 0.80 CYP1A2 (0.39) P2RX7ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL11758159 0.78 P2RX7 (0.35) P2RX7ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL5185360 0.73 ALDH1A1 (0.34) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL95103 0.70 CA1 (0.34) ALDH1A1
SCHEMBL7183711 0.70 CYP1A2 (0.39) P2RX7ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL7188455 0.70 ALDH1A1 (0.39) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL31574227 0.69 CA1 (0.33) ALDH1A1
SCHEMBL10873924 0.67 CES2 (0.32)
SCHEMBL10801092 0.67 GABRA1 (0.41) ALDH1A1CYP1A2
SCHEMBL11173889 0.65 P2RX7 (0.34) P2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4171456-A α,α'-Bis(2-hydroxyethoxy)-2,3,5,6-tetrabromo-p-xylene ETHYL CORPORATION (US) 1979-10-16 US disclosed