Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CDC7 | O00311 | 1/20 | 0.50 |
| ▸ | PLK4 | O00444 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | CHUK | O15111 | 1/20 | 0.50 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.50 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PAK4 | O96013 | 1/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | PRKCG | P05129 | 1/20 | 0.50 |
| ▸ | INSR | P06213 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 1/20 | 0.50 |
| ▸ | CDK1 | P06493 | 1/20 | 0.50 |
| ▸ | FES | P07332 | 1/20 | 0.50 |
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | LYN | P07948 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12967947 | 0.79 | TP53 (0.47) | MAPK1MAPTTP53CYP2C9CYP2C19 | |
| SCHEMBL11546004 | 0.75 | PSMB5 (0.43) | MAPTSOAT1ALDH1A1GABRPGABRD | |
| SCHEMBL7283175 | 0.73 | MAPT (0.51) | MAPK1MAPTTP53CYP2C9CYP2C19 | |
| SCHEMBL29150809 | 0.73 | SCN9A (0.44) | MAPTTP53CYP2C19CYP2D6KDM4E | |
| SCHEMBL29150813 | 0.73 | KDM4E (0.44) | MAPK1MAPTTP53CYP2C9CYP2C19 | |
| SCHEMBL10706756 | 0.70 | ADRB2 (0.65) | MAPK1TP53CYP2C9CYP2C19CYP19A1 | |
| SCHEMBL27670043 | 0.70 | LTA4H (0.63) | MAPK1MAPTCYP2C9CYP2C19CYP2D6 | |
| SCHEMBL4270583 | 0.70 | CNR1 (0.50) | MAPK1MAPTTP53CYP2C9CYP2D6 | |
| SCHEMBL15473241 | 0.70 | ALDH1A1 (0.42) | MAPK1MAPTTP53CYP2C9CYP2C19 | |
| SCHEMBL29150859 | 0.70 | CYP11B2 (0.46) | MAPTTP53GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4175191-A | 4-Phenyl isoquinolines | SANDOZ, INC. (US) | 1979-11-20 | — | — | US | disclosed |