Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11544932 | 0.79 | ACE (0.46) | ACERENDPP4SMN1; SMN2 | |
| SCHEMBL7380820 | 0.74 | ACE (0.54) | ACEREN | |
| Water SCHEMBL5570208 | 0.73 | ACE (0.52) | ACEREN | |
| SCHEMBL15854285 | 0.73 | ACE (0.62) | ACEREN | |
| SCHEMBL5742535 | 0.73 | ACE (0.62) | ACEREN | |
| SCHEMBL5742529 | 0.73 | ACE (0.62) | ACEREN | |
| SCHEMBL11548591 | 0.72 | ALDH1A1 (0.57) | ACESMN1; SMN2 | |
| SCHEMBL9501764 | 0.72 | ACE (0.55) | ACERENPOLBSMN1; SMN2 | |
| SCHEMBL21246658 | 0.72 | ACE (0.60) | ACEREN | |
| SCHEMBL21246655 | 0.72 | ACE (0.60) | ACEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154840-A | Antihypertensive pipecolic acid derivatives | E. R. SQUIBB & SONS, INC. (US) | 1979-05-15 | — | — | US | disclosed |
| US-4105776-A | ANGIOTENSIN CONVERTING ENZYME INHIBITORS, HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-08-08 | — | — | US | disclosed |