SCHEMBL115476

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16104427	0.86	C5AR1 (0.54)	KMT2AMEN1C5AR1PNMTCLPP
	SCHEMBL3719295	0.84	MEN1 (0.49)	KMT2AMEN1C5AR1CLPPALDH1A1
	SCHEMBL116582	0.83	KMT2A (0.64)	KMT2AMEN1C5AR1DHFRPNMT
	SCHEMBL15189144	0.79	KMT2A (0.63)	KMT2AMEN1C5AR1DHFRCLPP
	SCHEMBL116437	0.79	ALDH1A1 (0.51)	KMT2AMEN1C5AR1CLPPKDM4E
	SCHEMBL115543	0.78	AKT1 (0.51)	KMT2AMEN1C5AR1CLPP
	SCHEMBL3434578	0.78	ALDH1A1 (0.47)	KMT2AMEN1C5AR1CLPPKDM4E
	SCHEMBL1426066	0.78	C5AR1 (0.50)	KMT2AMEN1C5AR1DHFRCLPP
	SCHEMBL116629	0.77	LMNA (0.47)	KMT2AMEN1C5AR1CLPPKDM4E
	SCHEMBL16034465	0.77	KMT2A (0.53)	KMT2AMEN1C5AR1DHFRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.