SCHEMBL116629

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL116437	0.90	ALDH1A1 (0.51)	LMNABRS3POLBKDM4ESMN1; SMN2
	SCHEMBL3434578	0.87	ALDH1A1 (0.47)	LMNAPOLBKDM4ESMN1; SMN2C5AR1
	SCHEMBL115542	0.86	LMNA (0.50)	LMNAPOLBKDM4ESMN1; SMN2C5AR1
	SCHEMBL3524088	0.85	LMNA (0.47)	LMNAPOLBKDM4ESMN1; SMN2C5AR1
	SCHEMBL3434587	0.84	ALDH1A1 (0.58)	LMNABRS3POLBKDM4ESMN1; SMN2
	SCHEMBL167919	0.84	LMNA (0.46)	LMNAPOLBKDM4ESMN1; SMN2C5AR1
	SCHEMBL3528234	0.83	PRLHR (0.42)	LMNAALDH1A1GAA
	SCHEMBL3528638	0.81	MEN1 (0.37)	LMNAMAPK14KMT2AGAAMEN1
	SCHEMBL16104436	0.80	ALDH1A1 (0.42)	LMNAPOLBKDM4ESMN1; SMN2C5AR1
	SCHEMBL13076010	0.80	ALDH1A1 (0.48)	LMNABRS3KDM4ESMN1; SMN2C5AR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.