Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 4/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.40 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31694098 | 0.80 | SIRT2 (0.44) | DRD1DRD2MEN1KMT2ACYP3A4 | |
| SCHEMBL20850872 | 0.80 | DRD1 (0.43) | DRD1DRD2MEN1KMT2ACYP3A4 | |
| SCHEMBL8540341 | 0.80 | SLC6A2 (0.42) | DRD1DRD2MEN1KMT2ACYP3A4 | |
| SCHEMBL8537530 | 0.80 | DRD1 (0.56) | DRD1DRD2MEN1KMT2ACYP3A4 | |
| SCHEMBL11516181 | 0.79 | SLC6A2 (0.44) | SLC6A3 | |
| SCHEMBL6587573 | 0.79 | SLC6A3 (0.48) | MEN1KMT2ASLC6A3MAPTGAA | |
| SCHEMBL4001774 | 0.78 | MEN1 (0.52) | KIF11DRD1DRD2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11553849 | 0.77 | MEN1 (0.50) | DRD1DRD2MEN1KMT2ACYP3A4 | |
| SCHEMBL30720442 | 0.76 | SIRT2 (0.47) | ALOX12TRPM4TRPM5MEN1KMT2A | |
| SCHEMBL10539474 | 0.74 | ESR2 (0.44) | ALOX12KIF11TRPM4TRPM5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153789-A | HYPOGLYCEMIC AGENTS, ANTICOAGULANTS | DELMAR CHEMICALS LIMITED (CA) | 1979-05-08 | — | — | US | disclosed |
| US-4080330-A | HYPOGLYCEMIC AGENTS, ANTICOAGULANTS | DELMAR CHEMICALS LIMITED (CA) | 1978-03-21 | — | — | US | disclosed |