Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 5/20 | 0.39 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | DRD5 | P21918 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31694098 | 0.80 | SIRT2 (0.44) | MEN1KMT2ACYP3A4CYP2D6CYP19A1 | |
| SCHEMBL8537530 | 0.80 | DRD1 (0.56) | MEN1KMT2ACYP3A4CYP2D6DRD1 | |
| SCHEMBL20850872 | 0.80 | DRD1 (0.43) | MEN1KMT2ACYP3A4CYP2D6DRD1 | |
| SCHEMBL8543734 | 0.80 | HTR2A (0.46) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL11547755 | 0.80 | ALOX12 (0.43) | SLC6A3MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL5871368 | 0.79 | PRCP (0.42) | MEN1KMT2ACYP3A4CYP2D6MAPT | |
| SCHEMBL4001774 | 0.78 | MEN1 (0.52) | MEN1KMT2ACYP3A4CYP2D6DRD1 | |
| SCHEMBL2347871 | 0.78 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3MEN1KMT2A | |
| SCHEMBL8482343 | 0.77 | PKM (0.43) | SLC6A2SLC6A4SLC6A3KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL11553849 | 0.77 | MEN1 (0.50) | MEN1KMT2ACYP3A4CYP2D6DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721949-B1 | INDOLINE COMPOUND AND 5-HT 3? RECEPTOR ANTAGONIST CONTAINING THE SAME AS ACTIVE INGREDIENT | TOKYO TANABE CO (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5677326-A | GASTROINTESTINAL DISORDERS | TOKYO TANABE COMPANY LIMITED (JP) | 1997-10-14 | — | — | US | disclosed |
| EP-0721949-A1 | INDOLINE COMPOUND AND 5-HT 3? RECEPTOR ANTAGONIST CONTAINING THE SAME AS ACTIVE INGREDIENT | TOKYO TANABE COMPANY LIMITED (JP) | 1996-07-17 | — | — | EP | disclosed |