Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 10/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8537530 | 0.80 | DRD1 (0.56) | DRD1CYP3A4MEN1CYP2D6KMT2A | |
| SCHEMBL8540341 | 0.80 | SLC6A2 (0.42) | DRD1CYP3A4MEN1CYP2D6KMT2A | |
| SCHEMBL11547755 | 0.80 | ALOX12 (0.43) | DRD1CYP3A4MEN1CYP2D6KMT2A | |
| SCHEMBL31694098 | 0.80 | SIRT2 (0.44) | DRD1CYP3A4MEN1CYP2D6KMT2A | |
| SCHEMBL4001774 | 0.78 | MEN1 (0.52) | DRD1CYP3A4MEN1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL11553849 | 0.77 | MEN1 (0.50) | DRD1CYP3A4MEN1CYP2D6KMT2A | |
| Formamide SCHEMBL11551135 | 0.73 | MEN1 (0.44) | CYP3A4MEN1CYP2D6KMT2ATAAR1 | |
| SCHEMBL9764701 | 0.72 | DRD1 (0.70) | DRD1CYP3A4CYP2D6TAAR1DRD2 | |
| SCHEMBL6010798 | 0.71 | CYP3A4 (0.66) | DRD1CYP3A4MEN1CYP2D6KMT2A | |
| SCHEMBL15339313 | 0.71 | KDM1A (0.36) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915804-B1 | NOVEL AMINE DERIVATIVE OR SALT THEREOF AS TNF ALPHA INHIBITORS | FUJIFILM TOYAMA CHEMICAL CO LTD (JP) | 2019-03-27 | — | — | EP | disclosed |