Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 6/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.37 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.37 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.37 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.37 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20850872 | 0.80 | DRD1 (0.43) | CYP3A4MEN1KMT2ACYP2D6DRD1 | |
| SCHEMBL11547755 | 0.80 | ALOX12 (0.43) | CYP3A4MEN1KMT2ACYP2D6DRD1 | |
| SCHEMBL8537530 | 0.80 | DRD1 (0.56) | CYP3A4MEN1KMT2ACYP2D6DRD1 | |
| SCHEMBL8540341 | 0.80 | SLC6A2 (0.42) | CYP3A4MEN1KMT2ACYP2D6DRD1 | |
| SCHEMBL4001774 | 0.78 | MEN1 (0.52) | CYP3A4MEN1KMT2ACYP2D6DRD1 | |
| Hydrochloric Acid SCHEMBL11553849 | 0.77 | MEN1 (0.50) | CYP3A4MEN1KMT2ACYP2D6DRD1 | |
| SCHEMBL14094472 | 0.75 | SIRT2 (0.46) | SIRT2MEN1KMT2ACYP19A1HSD17B10 | |
| SCHEMBL14094474 | 0.75 | SIRT2 (0.66) | SIRT2MEN1KMT2AHSD17B10TP53 | |
| SCHEMBL22445693 | 0.74 | CYP3A4 (0.66) | CYP3A4MEN1KMT2ACYP2D6DRD1 | |
| SCHEMBL12836381 | 0.73 | DRD1 (0.37) | CYP3A4MEN1KMT2ACYP2D6DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025201477-A1 | SPIROCYCLIC GSDME INHIBITORS | PYROTECH (BEIJING) BIOTECHNOLOGY CO.,LTD. (CN) | 2025-10-02 | — | — | WO | disclosed |